Promethazine is the derivative of the phenothiazine. It is blocker of H1 receptor antagonist.It is also used in combination with other drugs to treat cough associated with respiratory problems
Each 5 ml contains:
Promethazine HCl 5 mg
Syrup
Antihistamine
Allergic Rhinitis, Anaphylactic Reactions, Motion Sickness, Pain, Sedation, Allergic Conjunctivitis, Nausea, and Vomiting.
Promethazine acts on the histamine receptors and blocks its activity therefore it is used in the treatment of allergic reactions, pain etc. Promethazine also acts on the muscarinic receptors and NMDA receptors to treat the sleep problems and anxiety and tension. Promethazine acts on the H1, dopamine and muscarinic receptors in the medullary vomiting centre and therefore used in the treatment of vomiting and nausea. It is orally absorbed and mainly bound to serum albumin and excreted via urine.
Promethazine is contraindicated in those patients with a known hypersensitivity to it or any of its ingredients or Promethazine.