Lactitol Monhydrate and Ispaghula Husk Granules

This combination is provided by combining a bulkforming laxative in the form of psyllium husk (Ispaghula husk) with an osmotic laxative such as lactitol for Idiopathic constipation and is used to prevent or treat constipation. Constipation is a common problem which can be caused by a number of things. Not eating enough fiber or not drinking enough fluid can cause constipation. Some conditions can cause constipation such as such as pregnancy or lack of exercise or movement (such as being ill in bed) or some medicines. It is a common problem for adults and pediatric patients and can generate considerable suffering for patients due to both the unpleasant physical symptoms and psychological preoccupations that can arise. In this combination, Lactitol is an osmotic disaccharide laxative that increases fecal volume and stimulates peristalsis. Ispaghula husk helps relieve constipation and as a laxative, works by increasing the bulk of stools, which encourages bowels to move the stools through digestive system, which in turn relieves constipation. Bulkforming laxatives absorb water and expand in the colonic lumen; in contrast, osmotic laxatives retain water in the colonic lumen by osmosis. So, both laxatives act to retain water in the colonic lumen thereby counteracting the normal dehydrating action of the colon. By suppressing the dehydration action of the colon, the osmotic laxative produces a fecal stream which is softer, bulkier and easier to expel. These laxatives also help to produce formed stools, without any systemic toxicity.