Dry syrups are the mixtures that require the addition of water at the time of dispensing inadequate chemical stability of drug in aqueous vehicle to avoid the physical stability problem. Cefpodoxime Proxetil Dry Syrup is a cephalosporin antibiotic. It is given as a Cefpodoxime proxetil. Cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime It is active against most Gram positive and Gram negative bacteria. It is commonly used to treat acute otitis media, pharyngitis, and sinusitis.
Each 5 ml contains:
Cefpodoxime 50 mg
Suspension
Antibiotic
It is Used to Treat Number of Bacterial Infections Including: Acute otitis media, Pharyngitis and/or tonsillitis, Community-acquired pneumonia, Acute bacterial exacerbation of chronic bronchitis, Acute, uncomplicated urethral and cervical gonorrhea, Acute, uncomplicated ano-rectal infections in women, Uncomplicated skin and skin structure infection, Acute maxillary sinusitis, and Uncomplicated urinary tract infections (cystitis).
The bactericidal activity of cefpodoxime results from its inhibition of cell wall synthesis. The active metabolite of cefpodoxime binds preferentially to penicillin binding protein 3, which inhibits production of peptidoglycan, the primary constituent of bacterial cell walls. Cefpodoxime proxetil is a prodrug that is absorbed from the gastrointestinal tract and de-esterified to its active metabolite, cefpodoxime.
Hypersensitivity reactions to cefpodoxime, other cephalosporins, penicillins, or other drugs. Contraindicated in Pregnancy and lactation in women, stomach and bleeding disorders.`