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Clobetasol & Combination

This composition is very effective to treat the problems or symptoms associated with skin diseases such inflammation, itching , redness and also to treat bacterial and fungal infections .this combination only use to the treats bacterial infections it is not recommended for viral infections.

  • Composition

    Chlorocresol 0.1% w/w
    Clobetasol Propionate 0.05% w/w
    Miconazole Nitrate 2.00% w/w
    Neomycin Sulphate 0.5% w/w

  • Release form

    Cream

  • Category

    For Derma Care

Indications

Used in psoriasis, dermititis, Lichen Planus- it is condition which causes irritation in the nails , mucous membrane etc., miconazole nitrate treats vaginal burning , itching caused by the vaginal yeast infection, and Neomycin sulphate also reduce the symptoms of hepatic coma.

Pharmacology

clobetasol propionate acts by blocking the metabolism of arachidonic acid and prevents the formation of inflammatory mediators which causes inflammation whereas neomycin sulphate interferes with bacterial protein synthesis by binding to 30S ribosomal subunits and miconazole may act by inhibiting the fungal enzyme 14α-sterol demethylase, resulting in a reduced production of ergosterol..

Contraindications

Patients with or without chronic asthma in whom attacks of asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid (as pirin) or other non-steroidal anti-inflammatory drugs (NSAIDs).

Side Effects

Hypersensitivity (including urticaria), angioneurotic oedema, Rash, eczema, erythema, dermatitis (including dermatitis contact), pruritus, Photosensitivity reaction.

Precautions & Warnings

Do not apply to open wounds or damaged skin, if symptoms persist for more than seven days discontinue use and consult physician,