Potassium Nitrate and Fluoride Gel

This composition is used together to reduce cavity and pain associated with the sensitize teeth here fluoride acts by reducing the tooth decay and potassium causes calming the nerve endings
  • De- sensitizing agent
  • Prevent cavities

Potassium Nitrate:

Potassium nitrate is used as de – sensitizing agent as it reduces the sensitization of the teeth. It is the component present in most of the toothpastes and mouth washes

Fluoride:

• Fluoride helps to prevent tooth decay.
• It is available in different formulations such as gels, toothpastes, rinses etc.

Mechanism of Action:

Potassium Nitrate works by inhibiting the transmission across the nerve endings by diffusing across the dentinal tubules and causes depolarization of the nerve endings thus it does not respond to external stimuli

Fluoride kills the bacteria which causes tooth decay; also, it inhibits the metabolic activity of the bacteria by which it produces lactic acid It also acts by absorbing on the surface of the hydroxyapatite crystals and causes mineralization and prevents demineralization

Pharmacokinetics:

Potassium Nitrate-
• It is absorbed in the small intestine
• It is metabolized in the gastrointestinal tract
• It is excreted via urine

Fluoride-
• It is absorbed by GIT
• It is bound to plasma proteins
• It is excreted via urine
  • Peeling of the skin
  • Upset stomach
  • Wheezing
  • Tightness in the chest
  • Hoarseness
  • Swelling of lips

Contraindication:

Contraindicated in people with known allergy.
  • Abacavir
  • Acebutolol
  • Acetaminophen
  • Aceclofenac
  • Acarbose

Storage:

Store it at room temperature.

Caution:

Keep it reach out of children