Oxetacaine,Aluminum hydroxide & Magnesium hydroxide Suspension

Oxetacaine is a potent local anesthetic. It is an amide anesthetic that is stated to have prolonged action. It is administered by mouth in conjugation with antacids; aluminum hydroxide and magnesium hydroxide, for symptomatic relief of pain associated with peptic ulcer disease (gastro-esophageal reflex disease).
  • Gastro-esophageal reflex disease
  • Peptic ulcer
  • Relief pain associated with hemorrhoids
  • Local anesthetic
  • Gastric/duodenal ulcer
  • Stomach discomfort
  • Heart burn in late pregnancy
  • Hyperacidity
  • Eructation.

PHARMACOKINETIC PROPERTIES

Onset of Action: 5 minutes
Duration of Action: 2-3 hours

PHARMACODYNAMIC PROPERTIES

Oxetacaine is a topical potent anesthetic. Combining Oxetacaine with aluminum hydroxide exerts a prolonged topical anesthetic action.
The antacid neutralize stomach acid and prevents further irritation of the food pipe.
Antacid containing aluminum hydroxide is contradicted in patients having low level of phosphate in blood (Hypophosphatemia) due to phosphate binding property of aluminum salt.
Contradicted in sever renal impairment.
Avoid long term use of this otherwise it will leads to Hypophosphatemia.
Caution
Drinking anything immediately after taking suspension should be avoided to prevent the Oxetacaine antacid suspension being washed away before the local anesthetic has had the desire effect.
  • Constipation
  • Rash
  • Thirst
  • Diarrhea
  • Headache
  • Anorexia
  • Weakness
  • Sleepiness
  • Vertigo
Keep bottle tightly closed in a cool place.