Miconazole Cream

This cream is also used to treat a skin condition known as pityriasis ( it is caused by virus ), it causes a lightening or darkening of the skin of the neck, chest, arms, or legs.
Miconazole is an azole antifungal drug which works by preventing the growth of fungus.
  • It is used to treat various skin infections like athlete's foot,infection caused by ringworm
  • Used in vaginal candidiasis.
  • Used to treat pityriasis
  • Used to treat jock itch

Mechanism of action:

Miconazole inhibits the enzyme 14-α demethylase, a cytochrome P-450 enzyme which converts lanosterol to ergosterol. As ergosterol is an essential component of the cell membrane of the fungus so inhibition of ergosterol prevents te cell walls synthesis.

  • It causes allergic reaction like rashs , itching, red, blistered, peeling of the skin
  • wheezing
  • tightness of the chest or throat
  • difficulty in breathing
  • hoarseness of voice
  • difficulty in swallowing
  • Irritation of the skin .

In case of genital candidiasis the fat present in the cream damages the latex in the condoms and diaphragms so there is no longer protection guaranteed.

Pregnancy: Miconazole is used to treat vaginal candidiasis generally during second and third trimester.
  • Store it at room temperature between 15ºC to 30ºC.
  • Store in cool and dry place.
  • Keep it reach out of children and pets.

Caution:

Miconazole is used with caution in nursing mother.