It belongs to the group of medicines known as 5-HT3 receptor antagonists or antiemetics. It contains the active ingredient Granisetron. It is used to prevent and treat nausea, vomiting, or sickness caused by cancer treatments such as chemotherapy, radiotherapy, or after surgery. Nausea is characterized by stomach pain and the urge to vomit. The forcible voluntary or involuntary emptying of the stomach's contents through the mouth is known as vomiting.
Granisetron Hydrochloride 3 mg
Injection
Antiemetics
For the prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy (including high dose cisplatin), postoperation, and radiation (including total body irradiation and daily fractionated abdominal radiation).
Granisetron is a potent, selective antagonist of 5-HT3 receptors. The antiemetic activity of the drug is brought about through the inhibition of 5-HT3 receptors present both centrally (medullary chemoreceptor zone) and peripherally (GI tract). This inhibition of 5-HT3 receptors in turn inhibits the visceral afferent stimulation of the vomiting center, likely indirectly at the level of the area postrema, as well as through direct inhibition of serotonin activity within the area postrema and the chemoreceptor trigger zone.
You are recommended to limit or avoid alcohol consumption while taking medication Granisetron 3mg injection. Alcohol intake, along with GRANISETRON INJECTION 3ML, may lead to unwanted side effects and cause increased dizziness.p>