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Clindamycin Phosphate, Clotrimazole and Tinidazole

This medication is used to treat vaginal yeast infections. Clotrimazole reduces vaginal burning, itching, and discharge that may occur with this condition. This medication is an azole antifungal. It works by stopping the growth of yeast (fungus) that causes the infection. The vaginal product comes in 2 forms (a vaginal cream or tablet). Some products come with a skin cream to be applied to the area around the outside of the vagina..

  • Composition

    Clindamycin Phosphate IP 100mg
    Eq. to Clindamycin Clotrimazole IP 100mg
    Tinidazole IP 100mg

  • Release form

    Soft gel

  • Category

    Women

Indications

  • Treatment of vaginal infections
  • Vaginal mycoses secondarily infected with bacteria
  • Vaginal and vulvo-vaginal infections

Pharmacology

Clindamycin is a lincosamide antibiotic with a primarily bacteriostatic action against Gram-positive aerobes and a wide range of anaerobic bacteria. Lincosamides such as clindamycin bind to the 50S subunit of the bacterial ribosome similarly to macrolides such as erythromycin and inhibit the early stages of protein synthesis. The action of clindamycin is predominantly bacteriostatic although high concentrations may be slowly bactericidal against sensitive strains.

Contraindications

Blood dyscrasias, Decreased neutrophils, Epileptic seizure, First trimester of pregnancy and Hypersensitivity.

Side Effects

Anorexia, Bitter taste, Nausea, Vomiting, Diarrhoea, Fatigue, Dry mouth, Abdominal distress & Headache.