About Composition

Berberine is a natural compound found in goldenseal, barberry, and other medicinal herbs. This safe, well-tolerated extract is as effective as prescription drugs for lowering blood sugar. Berberine, a plant alkaloid revered in traditional Chinese and Ayurvedic medicine is poised to become one of the most powerful natural therapies useful in a wide range of conditions - particularly insulin resistance and diabetes.
What Conditions Is Berberine Good For?
Anti-aging, Diabetes, Heart disease, High cholesterol, Hypertension (high blood pressure), Immune challenges, Intestinal infections, Joint problems, Low bone density, and Weight control.

Mechanism

Berberine targets a very basic and ancient regulator of metabolism called AMP-activated protein kinase (AMPK). Increased AMPK activity explains why berberine has so many diverse benefits.
For people with diabetes, AMPK activation:

• Stimulates the uptake of glucose into the cells
• Improves insulin sensitivity
• Reduces glucose production in the liver

The researchers concluded,"In summary, berberine is a safe, potent oral hypoglycemic [blood sugar lowering] agent with modest effect on lipid metabolism, blood pressure and weight.
As per in comparative study with metformin, berberine exhibited an identical effect in the regulation of glucose metabolism, such as HbA1c, FBG [fasting blood glucose], PBG [blood sugar after eating], fasting insulin and postprandial insulin [insulin level after eating]. In the regulation of lipid metabolism, berberine activity is better than metformin. Triglycerides and total cholesterol in the berberine group had decreased and were significantly lower than in the metformin group.

Precautions

Consult a medical doctor before taking this or any other nutritional supplements if you are pregnant, nursing, have or suspect a medical condition or are taking any medications.