Aceclofenac and paracetamol Suspension
Aceclofenac 50 mg
Paracetamol 325 mg
Paracetamol is a safe and effective analgesic-antipyretic agent with minimal effect on Cardiovascular , respiratory and GI system. Paracetamol is a widely used over-the-counter analgesic and antipyretic.
It has been demonstrated by recent studies of INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES that administration of combination (aceclofenac + paracetamol suapension) possesses remarkable anti-inflammatory, Analgesic and antipyretic properties.
- Pain and Inflammation
- Dental Pain
- Back Pain
- Inflammatory conditions of ear, nose & throat.
Absorption:-Aceclofenac: Rapidly absorbed; almost 100% bioavailability; peak plasma levels reached about 1.25-3 hours after oral admin.
Distribution:-Aceclofenac:>99.7% bound to plasma proteins; distributes into synovial fluid.
Paracetamol: Distributes throughout most fluids of the body.
Metabolism:- Aceclofenac:Probably metabolized by CYP2C9; average plasma elimination half-life: 4-4.3 hours.
Paracetamol: Mainly metabolized hepatically; plasma elimination half-life: 1-4 hours.
Excretion:-Aceclofenac: About two-thirds of the administered dose is removed in the urine, mainly as conjugated hydroxymetabolites.
Paracetamol: Most metabolites are removed in the urine within 24 hours.
- Nausea allergic reactions
- Skin rashes
Store in a well closed container in cool, dry place, away from direct heat and light.